Artisan Technology Group Quest 210 Specifications

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Quest 210 Limited Warranty Agreement Quest 21 0 Limited Warranty Agreement HOW LONG IS THE WARRANTY (TERM) This Warranty Agreement begins on the invoi

Introduction Quest 21 0 Limited Warranty Agreement EXCLUSIONS (WHAT IS NOT COVERED) This warranty covers normal use and is limited in scope to loss or

SITE PREPARATION 4. Shipment boxes or packaging used to package systems and accessories which are returned to the factory for repair. It is the custom

Introduction lnterference Information lnterference Information This equipment generates and uses radio frequency energy and, if not installed and used

Safety Safety This equipment has been tested and found to comply with the requirements as set forth in the European Immunity Standard: EN5OO82- 111 99

Introduction Contact lnformation Contact Information In the United States: Argonaut Technologies 887 Industrial Road, Suite G San Carlos, CA 94070 PHO

Quest 21 0 Technical Support Contact Information Quest 210 Technical Support Contact lnformation Quest 210 Repair Center and Technical Support Hotline

Introduction Quest 21 0 Overview Quest 210 Overview WARNING The Quest 210 Manual Synthesizer is designed for use in chemical synthesis including poten

Quest 21 0 Overview The solvent bottle assembly consists of a cap to interface to a 4 L solvent bottle. The Cap assembly will alternatively pressurize

Introduction Quest Installation Procedure Quest Installation Procedure Installation of the Quest involves connecting the system to a gas source, and m

User Manual Quest 2 1 0 Manual Synthesizer part number 900 1 14 Rev 3 ARGONAUT TECHNOLOGIES Artisan Technology Group - Quality Instrumentation ... Gua

Installation Procedure - Installation Procedure - Clear a space in a fume hood for the Quest. The space should be about 3 ft. wide by 2 ft. deep and

Introduction Quest Installation Procedure Figure 1-2 Quest Controller Unit - Umbilicus Connections Artisan Technology Group - Quality Instrumentatio

Figure 1-3 Quest Reactor Unit installation Procedure - QUEST 210 User Manual ain Port ~ons Poa Ins Ier Man1 Levers r Manifc Artisan Technology Group -

Introduction Quest Installation Procedure Connect the Umbilicus to the Quest Controller unit. Press the round male electrical connector labeled P2 on

Connect the Reactor Unit Manifold Tubes The Solvent Bottle Cap has 3 female ports oriented in a "Triangle." (see diagram) Figure 1-4 Solvent

Introduction Quest Installation Procedure The 3 female bulk head fittings for these tube connections are located near the manual valves towards the ed

Connect the Reactor Unit Manifold Tubes Figure 1-7 Quest Upper Reactor Assembly Install the three tubes on one side of the Quest Reactor Unit: Screw

Introduction Quest Installation Procedure Screw in the bushing for one end of the tube labeled "Man. Del." to the remaining red bulk head fi

Connect Power to the Unit Connect the male "Quick Connect" fitting to a long Tygon tube (found in the ship kit) which will lead to the labor

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System Overview The Quest 210 system consists of the reactor assembly, control box, solvent bottle assembly, and umbilicus. The reactor assembly conta

System Overview Reactor Assembly Reactor Assembly The reactor assembly provides the ability to do the following: Run up to 20 liquid or solid phase re

Reaction Vessels Reaction Vessels Reaction Vessels Each side of the Reactor Unit contains a reaction vessel bank where 10 vessels can be mounted, for

System Overview Reactor Assembly Reaction Mixing NOTE Agitation parameters are set using the Controller Unit. For instructions, see Operating the Que

Reaction Mixing NOTE The ability to control the solvent and gas flow in the reactor assembly allows one to solvent to the reaction vessels, drain was

System Overview Reactor Assembly Manifold Control Valves Each side of the reactor assembly contains two manifold control valves: Control Valve 1 (on l

Manual Solvent Additjon to the Reaction Vessels Product Collection- Utilizes the metered gas option to supply 10 psi gas to the upper manifold common

System Overview Reactor Assembly Solvent Bottle Assembly The solvent bottle assembly consists of a 4L Solvent Bottle, plastic Bottle Safety Carrier,

Reaction Vessel Waste Draining NOTE Change the solvent bottle frit once per week. When a flow path is created from the Solvent Bottle Assembly deliver

System Overview Reactor Assembly Waste Tray and Container The Quest is equipped with a rectangular glass container for waste collection. The glass was

Table of Contents Introduction System Overview Operating the Quest 2 10 Maintenance Troubleshooting (To be supplied) Appendix A. Glossary of Terms Ap

Controller Unit Controller Unit The Controller Unit contains an LCD screen, keypad, electronics and firmware to control the Quest. The Controller unit

System Overview Controller Unit LCD Screen and Keypad The Controller Unit LCD screen and keypad allow you to set the reaction temperature, temperature

LCD Screen and Keypad to specify the reaction vessel size (5 or 10 rnL). (Vessel size is important so the proper heating algorithm can be applied.) Mo

System Overview Controller Unit STARTISTOP Button From the Set Temperature display screen, the STARTISTOP button will start or stop the heaters. After

Control Box Connections to the Reactor Assembly Control Box Connections to the Reactor Assembly The control box has connections for the Umbilicus for

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Operating the Quest 21 0 This chapter provides step-by-step instructions for using the Quest 2 10 Manual Synthesizer to complete a liquid or solid pha

Operating the Quest 21 0 Remove Old Reaction Vessels NOTE Always wear gloves and eye protection when working with the Quest. 1. Raise the Upper Manif

Remove Old Reaction Vessels Figure 3-2 Using the reaction vessel mount as a fulcrum, twist the vessel to "break it" from the Lower Manifold

Operating the Quest 21 0 4. With your fingers, remove the vessel and discard in an appropriate waste container. The magnet can be removed from the &qu

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Installing New Reaction Vessels I --- Set Temperature - - A: 90C 1:00 OFF B : 60C 0.00 OFF RVSize 5mL 5mL b. Press the Forward button to move the cur

Operating the Quest 21 0 Figure 3-5 Reaction vessel and installation tool 7. Press down on the Insertion Tool to set the reaction vessel over the mal

Installing New Reaction Vessels Figure 3-6 Press the vessel into place 8. Repeat this procedure for each vessel. Figure 3-7 Proper installation of t

Operating the Quest 210 WARNING Always use frits in the reaction vessels, even if the reaction is solution phase. Frits prevent particulates from harm

Installing New Reaction Vessels Waste Tray and Container The Quest is equipped with a rectangular glass container for waste collection. The glass wast

Operating the Quest 21 0 Starting a Reaction Starting a Reaction This section explains how to do the following: Setting the reaction temperature, temp

Setting the Reaction Temperature, Time, and Agitation Setting the Reaction Temperature, Time, and Agitation You set the reaction temperature, time, an

Operating the Quest 21 0 Starting a Reaction 2. Set the Upstroke parameter. - The Upstroke parameter is the amount of time the agitation bar will be i

Setting the Reaction Temperature, Time, and Agitation 4. Set the Stroke Velocity. - If desired, modify the agitation speed by moving the control box

Operating the Quest 210 Starting a Reaction Temperature Control - The allowable reaction temperature range on the Quest is -40 to +130. For a particul

Introduction This manual is intended to assist you with operating and maintaining the Quest 210 Manual Synthesizer. This manual is organized into the

Temperature Control - Enter the Temperature Set-Point On the keypad, press the "Mode" button until the Set Temperature screen is displayed.

Operating the Quest 210 Starting a Reaction 9. Make sure that the vessel size selection in the Set Temperature screen matches the RV size that is bein

Temperature Control - b.Wrap teflon tape around the threads of both of the 1/16" elbow fittings exiting the cooling channel on both sides of the

Operating the Quest 210 Starting a Reaction Upper Manifold Membrane Switch In general set the Upper Manifold Membrane Switch to "Closed when runn

Parallel Solvent Addition and Vessel Draining on the solvent line and a Teflon bottle seal is present in the cap. Wait a minute or so for the bottle t

Operating the Quest 210 Starting a Reaction drain solvent closed utility 1 metered gas vent 0 closed utility 2 Artisan Technology Group - Quality Ins

Parallel Solvent Addition and Vessel Draining Draining the Reaction Vessels Reaction Vessel draining is typically done during solid phase synthesis du

Operating the Quest 210 Starting a Reaction Changing a Solvent Bottle Changing the 4L solvent bottle involves back-flushing the solvent delivery line,

Parallel Solvent Addition and Vessel Draining 6. Wait 5 seconds, then set the Manifold Control Valves to the following configuration. This will use th

Operating the Quest 210 Starting a Reaction Adding Solvent or Reagents Through the Luer Ports Solvents, liquid reagents and solids can be added to the

Introduction Quest 21 0 Specifications Quest 21 0 Specifications REACTION VESSELS AGITATION COLLECTION RACK DIMENSIONS Reactor Assembly (W xdx h) Wei

Providing a Gas Sweep over the Reaction Vessels 5. Replace the luer plug onto the solid entry port. 6. Place both Manifold Control Valves to "Clo

Operating the Quest 21 0 Starting a Reaction To stop the gas flow set the Manifold Control Valves as follows: drain solvent closed utility 1 metered

Collection of Liquid Reaction Products 1. Toggle the "Upper Manifold Membrane" switch to "Open." 2. Prior to product collection, i

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Maintenance This section explains how to clean the Quest System after a synthesis has been completed. Perform three solvent washes (solvent delivery,

Maintenance appropriate solvent. Do not allow any particulates to enter the through holes on the lower manifold male reaction vessel fittings. 7. Empt

5 Troubleshooting To be provided QUEST 210 User Manual Artisan Technology Group - Quality Instrumentation ... Guaranteed | (888) 88-SOURCE | www.artis

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Glossary of Terms Agitation - The Quest agitation system consists of a pneumatically actuated Magnet Bar which vertically oscillates behind the two r

Glossary of Terms Luer Ports - Found at the top of each Upper Manifold. Each port is a beveled hole with a corresponding plug. Solvents, reagents, an

Symbols Symbols The following hazard symbols are found on the Quest 210 Instrument: When heating, the Reactor Assembly will become hot. The symbol at

Upper Manifold - The upper manifold is an aluminum and telfon block that contains two common pathways: one for parallel solvent delivery drain gas, th

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Appendix B: Control Box Display Screens The display is a LCD screen on the control box. Some display screens allow you to view reaction temperature, t

Appendix B: Control Box Display Screens Figure 2-1 Quest Controller Box and LCD Display Artisan Technology Group - Quality Instrumentation ... Guarant

Sign-on Screen Sign-on Screen Quest 210 Argonaut Technologies The Sign-on screen identifies this instrument as the Argonaut Technologies' Quest 2

Appendix B: Control Box Display Screens Firmware Version Screen Firmware Version Screen ---- Quest 210 - - - - Rev : 1.00 Date: Dec 1, 1997 The Firmw

Agitation Control Screen Agitation Control Screen MixEvery : 2.0 sec UpStroke : 1.0 sec % Upward : 50 % I-- Not Agitating - - - The Agitation Control

Appendix B: Control Box Display Screens Agitation Control Screen Notice that the agitation parameters that you set apply to both Side A and B. Table 2

Set Temperature Screen Set Temperature Screen I --- Set Temperature - - A: 90C 1:00 ' OFF B : lOOC 0.00 OFF RV's A: 5mL B: 10 mL The Set t

Appendix 6: Control Box Display Screens Monitor Temperature Screen Monitor Temperature Screen SET ACT A(0ff) B (Off) The Monitor Temperature screen sh

Introduction User Supplied ltems - Quest 21 0 Manual Synthesizer User Supplied ltems - Quest 210 Manual Synthesizer 30 - 40 psi house nitrogen supply

Other Functions Screen Other Functions Screen I-- OTHER FUNCTIONS - 1. Proceed to Main 2. Adjust LCD 3. Show Fmwr Version The Other Functions scree

Appendix B: Control Box Display Screens Other Functions Screen Table 2-5 Other Functions Screen Control Button Functions The screen choice (1-5) indic

Contrast Control Screen Contrast Control Screen . . . Set Contrast , . . ------- 3- The Contrast Control Screen allows you to adjust the contrast o

Appendix B: Control Box Display Screens Self Test Screen Self Test Screen - - Self Test---- 100% A/D =OK TC = OK OK XFMR=OK HTR= OK OK v: --00000

Self Test Screen Table 2-7 SelfTest Screen Button Functions I Return to the Other Functions Screen. Pressing this button.,. STARTISTOP I STARTISTOP He

Appendix B: Control Box Display Screens Restore Defaults Screen Restore Defaults Screen This screen appears momentarily, after the Mode button is pres

Start/Stop Heaters Screen StartEtop Heaters Screen Stop Both A and B Start A A (is now OFF) Start B B (is now OFF) The Stop Heaters screen allows yo

Appendix C - QUEST 2 10 Plumbing Schematic Artisan Technology Group - Quality Instrumentation ... Guaranteed | (888) 88-SOURCE | www.artisantg.com

Artisan Technology Group is your source for quality new and certied-used/pre-owned equipment• FAST SHIPPING AND DELIVERY• TENS OF THOUSANDS OF IN-S